News & Pubs

Scientific and Medical Publications

59th American Society of Hematology (ASH) Annual Meeting and Exposition, Atlanta

  • Long-term follow up after adoptive transfer of CD19-specific CAR+T cells genetically modified via non-viral Sleeping Beauty system following hematopoietic stem cell transplantation (HSCT)
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  • CD19-specific chimeric antigen receptor-modified T cells with safety switch produced under “Point-Of-Care” using the Sleeping Beauty system for the very rapid manufacture and treatment of B-cell malignancies
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  • Autologous T cells modified to co-express CD33-specific chimeric antigen receptor and a kill switch for treatment of CD33+ acute myeloid leukemia
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  • Shortening the time to manufacture CAR+T cells with Sleeping Beauty system supports T-cell engraftment and anti-tumor effects in patients with refractory CD19+ tumors
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